Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection
نویسندگان
چکیده
منابع مشابه
Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV-infection.
BACKGROUND Pneumocystis jiroveci pneumonia (PCP) remains the most common opportunistic infection in patients infected with the human immunodeficiency virus (HIV). Among patients with HIV infection and PCP the mortality rate is 10 to 20% during the initial infection and increases substantially with the need for mechanical ventilation. It was suggested that in these patients corticosteroids adjun...
متن کاملAdjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection: a meta-analysis of randomised controlled trials
BACKGROUND The objective of this study was to review the effects of adjunctive corticosteroids on overall mortality and the need for mechanical ventilation in HIV-infected patients with Pneumocystis jiroveci pneumonia (PCP) and substantial hypoxemia (arterial oxygen partial pressure <70 mmHg or alveolar-arterial gradient >35 mmHg on room air). METHODS We conducted a systematic search of the l...
متن کاملAdjunctive steroid in HIV-negative patients with severe Pneumocystis pneumonia
BACKGROUND High-dose steroid therapy has been proven effective in AIDS-related Pneumocystis pneumonia (PCP) but not in non-AIDS-related cases. We evaluated the effects on survival of steroids in HIV-negative patients with PCP. METHODS Retrospective study patients admitted to the ICU with hypoxemic PCP. We compared patients receiving HDS (≥1 mg/Kg/day prednisone equivalent), low-dose steroids ...
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OBJECTIVE The purpose of this essay is to review the spectrum of high-resolution CT findings of Pneumocystis jiroveci pneumonia in immunocompromised patients with and without HIV infection. CONCLUSION Pneumocystis jiroveci pneumonia is a common opportunistic infection affecting immunosuppressed patients. High-resolution CT may be indicated for evaluation of immunosuppressed patients with susp...
متن کاملFPIN's clinical inquiries. Corticosteroids for presumed pneumocystis pneumonia in patients with HIV infection.
Evidence Summary A Cochrane meta-analysis of six RCTs (n = 489) found that corticosteroids given as early adjunctive anti–pneumocystis pneumonia therapy in patients with HIV infection decrease mortality at one month (risk ratio [RR] = 0.56; 95% confidence interval [CI], 0.32 to 0.98) and at three to four months (RR = 0.68; 95% CI, 0.5 to 0.94).1 Of the 489 patients, 463 had confirmed pneumocyst...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2015
ISSN: 1465-1858
DOI: 10.1002/14651858.cd006150.pub2